Design and Synthesis of Some Amino Coumarin Derivatives by Using Mild Catalyst
ثبت نشده
چکیده
Coumarin possesses a number of biological activities like antimicrobial, anti-inflammatory, analgesic, antioxidant, anticancer, antimalarial etc. Coumarin belongs to a group of benzpyranes, which consist of a benzene ring joined to a pyran nucleus. In the present study amino derivatives bearing coumarin nucleus are synthesized from 7-hydroxy -4methyl coumarin by using mild catalyst, CAN which is water soluble salt. The formed compounds have been evaluated by physical methods like melting point, thin layer chromatography, elemental analysis and functional group analysis.
منابع مشابه
Synthesis of 4-(trifluoromethyl) coumarins using nano sulfated-titania as solid acid catalyst under solvent-free conditions
Nano sulfated titania was tested as solid acid heterogeneous catalyst for the synthesis of 4-(Trifluoromethyl) coumarin and coumarin derivatives under solvent-free condition. Factorial design evidenced a positive effect of reaction temperature, amount of catalyst, and solvents. This nano-sized sulfated titania has been prepared by a sol-gel hydrothermal process. The prepared sulfated titania s...
متن کاملSynthesis of 4-(trifluoromethyl) coumarins using nano sulfated-titania as solid acid catalyst under solvent-free conditions
Nano sulfated titania was tested as solid acid heterogeneous catalyst for the synthesis of 4-(Trifluoromethyl) coumarin and coumarin derivatives under solvent-free condition. Factorial design evidenced a positive effect of reaction temperature, amount of catalyst, and solvents. This nano-sized sulfated titania has been prepared by a sol-gel hydrothermal process. The prepared sulfated titania s...
متن کاملA One-Pot Synthesis of Some Novel Ethyl 2-((1H-Benzo[d]imidazol-2-ylamino)(Aryl)methylthio)acetates by Nano-CuY Zeolite as an Efficient and Eco-Friendly Nanocatalyst
A one-pot multicomponent reaction of aryl aldehydes, 2-amino benzimidazole and ethyl 2-mercaptoacetate is described as an efficient and environmentally method for the synthesis of some novel ethyl 2-((1H-benzo[d]imidazol-2-ylamino)(Aryl)methylthio) acetates in the presence of nano-Copper Y Zeolite (NCZ) as a catalyst in ethanol at room temperature. After optimizing of r...
متن کاملRecyclable Boron Sulfonic Acid as an Environmentally Benign Catalyst for the One-Pot Synthesis of Coumarin Derivatives under Solvent-Free Condition
A mild and green method has been developed for the preparation of coumarins derivatives through the one-pot reactions. In our study,various phenols and ethyl acetoacetate compound in which we used silica-supported boron sulfonic acid [SiO2/B(SO4H)3] as a new, highly efficient and tri-functional inorganic Brønsted acid catalyst were processed under solvent-free condition and thermal. The catalys...
متن کاملA green approach for the synthesis of 2-amino-4H-chromene derivatives using Polystyrene-Supported 1-Methylimidazolium tetrachloroferrate as an efficient heterogeneous catalyst in water
In this study, we reported facile and efficient synthesis of 2-amino-4H-chromenes that catalyzed by polystyrene-supported 1-methylimidazolium tetrachloroferrateas. The synthesis proceeds with various aldehydes under mild conditions and afford the target products with good to high yields.
متن کامل